Wentzville Tobacco Company Factory was a historic tobacco factory located at Wentzville, St. Charles County, Missouri.

It measured approximately 40 feet by 90 feet and had a gable roof with long shed dormers.

[2]: 2 Despite being listed on the National Register of Historic Places in 1990, the historic building was demolished in 2002 and replaced with a parking lot.

A historic marker was placed next to the parking lot on the site of the former building.

This article about a property in St. Charles County, Missouri on the National Register of Historic Places is a stub.