Wesley is an unincorporated community and census-designated place (CDP) in western Madison County, Arkansas, United States.

Wesley is located at the junction of Arkansas highways 74 and 295, 13 miles (21 km) by road west-southwest of Huntsville.

[4] Wesley has a post office with ZIP code 72773.

[5] It was first listed as a CDP in the 2020 census with a population of 161.

This article about a location in Madison County, Arkansas is a stub.