He was Professor of histology and embryology and Chair of the Department of Anatomy at the University of North Carolina at Chapel Hill from 1940 to 1949.
George is remembered for his 87-page pamphlet, The Biology of the Race Problem, printed for the Commission of the Governor (John Patterson) of Birmingham, Alabama, 1962.
He saved special venom for Franz Boas and the Boasian physical anthropologists who argued that race was of no biological consequence.
[6] After the 1954 Supreme Court Brown v. Board of Education decision, George's fight against school integration escalated, reaching its height in 1955 - 1957, when George was active in the Patriots of North Carolina and then in the North Carolina Defenders of States' Rights which picked up the anti-integration banner after the Patriots' demise.
A 1961 article in The Citizens' Council quoted George as saying,[7] We badly need the states to establish and support offices to present the evil side of race amalgamation ... we have truth and virtue on our side.George served on the Executive Committee of the International Association for the Advancement of Ethnology and Eugenics.