The West Berkshire–Frelighsburg Border Crossing is located in a rural area of central northern Vermont and southern Quebec.

Quebec Route 237 runs south from Frelighsburg, roughly paralleling the northbound course of the Pike River to its west.

The United States station is located about 200 feet (61 m) south of the border, on the west side of the road.

The United States station is a rectangular brick building, 1+1⁄2 stories in height, with a wooden-frame side gable roof.

Its construction was prompted by an increase in automobile traffic, and a rise in smuggling activities occasioned by the years of Prohibition in the 1920s, and illegal immigration across the northern border.