Thomas Setrop Amos, a London solicitor, who arrived in Sydney in 1816, was granted 800 acres (3.2 km2) in this area in June 1818.

Other languages spoken at home included Arabic 8.9%, Hindi 4.7%, Spanish 3.4%, Assyrian Neo-Aramaic 3.3% and Vietnamese 3.2%.

The overseas-born population in West Hoxton includes those from Europe, as well as from more recent arrivals from Asia and the Pacific.

West Hoxton has a higher share of the population born in the Philippines, Fiji and Italy compared to the rest of the City of Liverpool.

Transit Systems operate four bus services routes 851, 852, 853 and 854, running along Cowpastures Road, connecting West Hoxton to Liverpool.