West Manchester is a village in Preble County, Ohio, United States.

According to the United States Census Bureau, the village has a total area of 0.27 square miles (0.70 km2), all land.

21.0% of all households were made up of individuals, and 7.2% had someone living alone who was 65 years of age or older.

The racial makeup of the village was 99.08% White, 0.46% Native American, 0.46% from other races.

22.0% of all households were made up of individuals, and 8.3% had someone living alone who was 65 years of age or older.

The National Trail Local School District serves students in West Manchester along with surrounding Monroe Township.