The main structure, built in 1922–1923, was a three-story red brick building in the Classical Revival style.

The school moved back to Huntington in 1903 following the purchase of 210 acres by Reverend McGhee on the city outskirts overlooking the Guyandotte River.

The original three-story building, which had been built in 1904 in part by the children's labor, experienced a fire on November 5, 1909.

A separate institution, the State Industrial Home for Colored Girls, was established in a building constructed on the property between 1924 and 1926, also of three stories.

[6] By 1951, residents of the Children's Home were no longer educated on site, but were bused to segregated public schools.

[7] The property was purchased by a mental health and addiction treatment group in 2008 and transferred to Cabell County Board of Education in 2009.

The building was demolished beginning on May 5, 2011,[8] over the objections of preservationists, in preparation for the construction of Huntington East Middle School.