West Virginia Route 41 (WV 41) is a 64.8-mile-long (104.3 km) north–south state highway in the central part of the U.S. state of West Virginia.

Its southern terminus is at WV 210 in Beckley.

Its northern terminus is at WV 55 about 1 mile (1.6 km) west of Calvin.

South of Summersville, WV 41 follows the route of U.S. Route 19 (US 19) prior to the construction of Corridor L of the Appalachian Development Highway System.

This West Virginia road or road transport-related article is a stub.