The Prix de West Artists sell original works of art as a fund raiser for the museum.

Its over 200 works by Charles Marion Russell, Frederic Remington, Albert Bierstadt, Solon Borglum, Thurmond Restuettenhall, Robert Lougheed, Charles Schreyvogel, and other early artists lead to the museum's prize collection of contemporary Western art created over the last 30 years by award-winning Prix de West artists.

The collection also includes over 700 pieces by Edward S. Curtis, and over 350 from Joe De Yong, along with the large plaster sculpture of James Earle Fraser's End of the Trail.

Visitors can stroll the streets, peek in some of the store windows, listen to antique player pianos, and actually walk into some of the fully furnished buildings.

The town comes alive with historical figures once a year during the museum's annual holiday open house, "A Night Before Christmas".

[1] In September 2022, it was announced that the museum's American Rodeo Gallery would house the Professional Bull Riders Hall of Fame.

[3] Every year, during the Western Heritage Awards, the museum awards the Bronze Wrangler, an original bronze sculpture by artist John Free, to principal creators of the winning entries in specified categories of Western literature, music, film, and television.

Past winners have included Owen Wister, William S. Hart, Tom Mix, Hoot Gibson, Ken Maynard, Tim McCoy, Harry Carey, John Kent Harrison, Roy Rogers, Gene Autry, Tex Ritter, Rex Allen, John Wayne, Randolph Scott, Joel McCrea, Richard Widmark, James Stewart, Buck Taylor, Howard R. Lamar, Ben Johnson, Pernell Roberts, Arthur Allan Seidelman, Skeet Ulrich and Tom Selleck.