The hospital was designed by California architect William Henry Weeks and funded by merchant Lin Walker Wheeler.

[5] During the economic challenges of the Great Depression, city-sponsored development initiatives continued to thrive throughout the latter part of the 1930s, through financial support from influential Gilroy families such as the Wheelers.

Every room and department within this new building featured a wall plaque denoting a memorial contribution from various sources, including individuals, families, businesses, employee groups, and clubs.

It was constructed from reinforced concrete and features, stucco siding, and decorative ceramic tile, and wrought iron elements on the front facade.

The central section of the building consists of two stories, with a second-story recessed loggia situated above a double-arched, tiled entryway.

The upper floor, spanning approximately 1,300 square feet (120 m2), originally served as the nurses' quarters and featured five bedrooms, two fully tiled baths, and a sitting room with a balcony overlooking the main entrance.

The building's exterior walls are primarily stucco, with ceramic tile embellishments located beneath the windows on the north side.

The ground plan's east wing accommodated surgery suites, an emergency room, a dining area, and the primary kitchen.