Sue (Jane Lynch) accepts a student with Down syndrome (Lauren Potter) onto the cheerleading squad, and Kurt (Chris Colfer) and Rachel (Lea Michele) compete for a solo performance.
"Defying Gravity" was included as a reflection of Colfer's own high school experience, which saw his drama teacher refuse to allow him to sing the song because of his sex.
"Wheels" was watched by 7.35 million US viewers, and saw Barclay nominated for the Directors Guild of America Award for Outstanding Directing of a Comedy Series.
The episode received generally positive reviews from critics, with Entertainment Weekly's Tim Stack and Aly Semigran of MTV both writing that it brought them to tears.
Will encourages the other club members to support Artie, not only by holding a bake sale to raise funds for a handicap bus, but also by spending time in wheelchairs to experience what life is like for him.
Meanwhile, Quinn Fabray (Dianna Agron) is struggling to cover the medical expenses of her pregnancy, and threatens to break up with Finn Hudson (Cory Monteith) if he cannot pay her ultrasound bill.
Burt receives an anonymous abusive phone call about his son's sexual orientation, and Kurt deliberately sabotages his own audition to spare his father further harassment.
The two go on a date and kiss, but part on bad terms when Tina confesses that she has been faking her speech impediment since the sixth grade, in order to deflect attention from herself, but now feels she no longer needs to, having been given confidence by the glee club.
Having previously removed Quinn from the cheerleading squad due to her pregnancy, coach Sue Sylvester is forced to hold open auditions to find a replacement.
"[4] Murphy commented that the episode caused him to realize that, as well as highlighting the "fun and glamour" of glee clubs, it is also occasionally "really great [...] to show the underbelly of what people who are different feel.
"[4] Recurring characters who appear in the episode are Kurt's father Burt Hummel (O'Malley), glee club members Brittany (Heather Morris), Santana Lopez (Naya Rivera), Mike Chang (Harry Shum, Jr.) and Matt Rutherford (Dijon Talton), school reporter Jacob Ben Israel (Josh Sussman), Principal Figgins (Theba) and former glee club director Sandy Ryerson (Stephen Tobolowsky).
"Wheels" guest stars Cheryl Francis Harrington and Jeff Lewis as a nurse and manager at a local residential facility, and also introduces two characters with Down syndrome, Robin Trocki as Sue's sister Jean Sylvester, and Lauren Potter as Becky Jackson, a sophomore at William McKinley High School.
[7] Glee cast versions of the songs, including both Michele and Colfer's solo performances of "Defying Gravity", were all released as singles available for digital download.
Murphy selected "Defying Gravity" for the episode after Colfer relayed a story from his own high school days, whereby his drama teacher refused to let him sing the song because of his sex.
"[20] Glee's executive producer Brad Falchuk responded that while he understood the concern and frustration of disability advocates, McHale had the singing and acting ability and charisma required for the role and: "it's hard to say no to someone that talented".
"[3] Gerrick Kennedy of the Los Angeles Times expressed a similar sentiment, stating: "Here we have an episode bluntly addressing the complexities of disability and doing so with so much respect and dignity, and there are complaints about Artie not being wheelchair-bound [sic] in real life?
[23] MTV's Aly Semigran also commented that the episode brought her to tears, suggesting that Lynch's performance was Emmy-worthy and deeming "Wheels" "a truly standout hour of TV".
[24] Raymund Flandez of The Wall Street Journal reviewed the episode positively, calling Artie's rendition of "Dancing With Myself" "catchy" and "upbeat" and praising Rachel's "Defying Gravity" audition, which he wrote: "leaves us wanting for more.
"[25] Kennedy described the episode as "sheer perfection",[22] and James Poniewozik of Time made the pun: "Glee's always been a pleasure, but if it raises its storytelling ambitions this way, it can really defy gravity.
"[26] Alan Sepinwall of The Star-Ledger wrote that while he generally finds Glee to be "a show with a serious identity crisis", he did not dislike "Wheels" as much as previous episodes.
He thought that having Kurt sabotage his own audition sent out a "mixed message", and believed that actress Lauren Potter was "used as a prop in the continuing humanization of Sue Sylvester."