[5] White-tailed prairie dogs display Interspecific competition with the Wyoming ground squirrel.

Female white-tailed prairie dogs who killed squirrels had increased litter sizes, but the higher her body count, the lower her chances of surviving each subsequent attack.

The female white-tailed prairie dogs and their pups are sedentary, meaning they stay close to or inside the burrow, while the male seeks the food.

It is subject to population controls by humans (shooting and poisoning), and threatened by a disease called Sylvatic Plague that can infect all prairie dogs.

[1] Petitions have been made to protect the white-tailed prairie dog, but they have been denied by the United States Fish and Wildlife Service due to insufficient scientific data describing current population trends.