Newsweek magazine ranked White Station #1027 in the United States and #8 in Tennessee in its 2009–2010 edition of America's Best High Schools.

White Station offers several foreign language options for students, including Spanish, Latin, Japanese, French and Mandarin Chinese.

In February 2022, White Station was announced to be one of 60 schools piloting the AP African American Studies Program.

The Lady Spartans tennis team has won the city championship for 3 consecutive years, 2009–2011, and finished as state runner-up in 2009, 2010, and 2011.

Additionally, the White Station High School cross-country teams sent 3 runners to the Tennessee Cross Country State Championships this year; they were Jarryn Lowe, Russell Wolfe, and Gabrielle Shirley.

[10] In 2013 the Spartan football team made it to 6A state semifinals, a game they lost 49–41 to Hendersonville High School.

White Station has many active clubs in areas including foreign language, mathematics, science, business, government, music, art, film and community service.

[citation needed] Additionally, they annually host a conference at White Station High in September, garnering attendance from various schools across the Mid-South.

[citation needed] Other activities include an elected student council, jazz ensemble, DECA, and HOSA club.

Students staff the school newspaper (The Scroll), the yearbook (The Shield), and an art and literary magazine (The Scribbler).

[citation needed] White Station's choir program has performed at events such as the Tennessee Holocaust Day of Remembrance and the TMEA conference.

[citation needed] In 2014, the White Station Men's Chorus was selected to perform at Southern division ACDA in Jacksonville, Florida.

[citation needed] White Station has a theatre program, including troupe 1581 of the International Thespian Society.

In addition to students from the surrounding neighborhood and who travel from all over the city for the school's college preparatory program, White Station serves the family housing units of the University of Memphis at the Park Avenue Campus.

[14][15][16] White Station can trace its origins to a school organized just prior to the Civil War that initially shared a building with a Masonic Lodge.

At that time, the Memphis City Board of Education foresaw the need for a separate junior and senior high school in the area to accommodate the growing population.