Wieke Paulusma (born 5 December 1978) is a Dutch health professional and politician for the social liberal party Democrats 66 (D66), who has been serving as a member of the House of Representatives since the 2021 general election.

[3][8] Paulusma then served as a partner at MAD Multimedia and a senior account manager at Storm Marketing Consultants.

She worked as a manager and project leader at Treant Zorggroep in 2017 before becoming a district nurse again the following year at TSN Thuiszorg.

[12][23] Paulusma also won the European Innovation in Politics Award for Democracy in 2019 for her work on the cooperative district council.

[31] In the House, she drew attention to long COVID, a condition from which she was suffering as a result of her coronavirus infection, and offered an action plan to Minister for Medical Care Tamara van Ark.

[30] Following the swearing in of the fourth Rutte cabinet in January 2022, her specialties changed to the coronavirus, curative care, and medicine.

[31] She defended her party's position to keep open the option of instating a 2G policy, under which only vaccinated or recovered people are allowed to enter certain places, to fight the COVID-19 pandemic.

[33][34] When the health minister was considering closing two of the four locations in the Netherlands for pediatric heart surgery for the sake of centralization, Paulusma filed a motion in February 2022 to force the investigation to take regional spread into account.

[35] Another motion of Paulusma was carried to send free self-tests to women to detect the human papillomavirus (HPV), which can lead to cervical cancer.

[38] A motion by Paulusma was passed in September 2024 calling on the government to donate 13,200 of its 100,000 mpox vaccines to African countries in response to the an epidemic.