Wiesbach lies in a depression of the Sickingen Heights (German: Sickinger Höhe) at the confluence of several streams called 'Wiesbach'.

As late as 1608 before the Thirty Years' War 110 people lived in Wiesbach (16 men, 15 women, 68 children, 11 servants and maids).

After the end of Thirty Years' War, many families from Tyrol, Switzerland, the Allgäu and Lorraine immigrated until 1670.

Wiesbach belonged until 1589 to the House of Sickingen at Nanstein Castle in Landstuhl and then came to Palatine Zweibrücken, where it remained until the end of the 18th century.

Soldiers of the Régiment de Royal Deux-Ponts (Deux-Ponts is French for Zweibrücken) fought in 1781 at the battle of Yorktown on the side of the French-American troops under the command of Comte de Rochambeau and George Washington against the British army.