Wilberforce is a census-designated place (CDP) in Greene County, Ohio, United States.

After Wilberforce College was established in 1856, the community was also named for the English statesman William Wilberforce, who worked for the abolition of slavery and achieved the end of the slave trade in the United Kingdom and its empire.

[4] The small community served as an important stop for refugee slaves on the Underground Railroad before the American Civil War, as it had seven stations.

[5] The Ohio Historical Society operates the National Afro-American Museum and Cultural Center, which provides exhibits and learning opportunities for the regional community.

On April 3, 1974, during the 1974 Super Outbreak, a destructive F5 tornado moved through the area after exiting the nearby city of Xenia, where it destroyed many homes and businesses.

Central State University also sustained significant damage, and a water tower was toppled.

In 1863 the AME Church sold another property in order to buy the college after its temporary closing due to financial problems during the war.

Bishop Daniel Payne, who led the founding and later purchase of the college, was its first president and served for many years.

Born into slavery, Young became the highest-ranking African-American officer in the US Army, a status that lasted until after World War I.