Wilderness is an unincorporated community in northeast Oregon County, in the U.S. state of Missouri.

[1] The community is at the end of Missouri Route K within the Irish Wilderness area of the Mark Twain National Forest.

[2] A post office called Wilderness was established in 1882, and remained in operation until 1954.

[3] The community derives its name from a region originally called "Irish Wilderness", a former Irish colony which was abandoned on account of Civil War violence.

This Oregon County, Missouri state location article is a stub.