Wiley Mayne (January 19, 1917 – May 27, 2007) was an American attorney who served as a four-term Republican United States Congressman from Iowa's 6th congressional district.

After a three-year tour of duty with the United States Naval Reserve as a lieutenant junior grade from 1941 to 1943, Mayne returned to private practice, joining a Sioux City, Iowa, law firm.

[3] In 1966, Mayne ran for Congress in the now-obsolete Sixth Congressional District in Northwest Iowa and defeated Democratic freshman incumbent Stanley L.

While serving on the House Agriculture Committee, a major issue of the era was a sudden and swift decline in the United States cattle market.

[5] As a member of the House Judiciary Committee, Mayne played an influential role in amendments to the Federal Rules of Evidence, especially those involving the admissibility of opinion testimony.