[2] Louise Creighton, a women's rights activist and author, and Alfred de Glehn, a French steam locomotive designer, were Alexander's sister and brother.

[4] In 1891, he was hired by Edwin Austin Abbey and John Singer Sargent to assist them on their Boston Public Library mural project at Morgan Hall.

Following their wedding, the couple honeymooned in Cornwall, England, vacationed in Paris and Venice, and made a permanent home in Chelsea, London.

When World War 1 intervened, husband and wife joined the staff of a British hospital for French soldiers, Hôpital Temporaire d'Arc-en-Barrois, Haute-Marne, France in January 1915, working for the Franco-British Red Cross.

Although some experts rank de Glehn alongside Sargent, he is considered as something of a late British Renoir, for his deft use of sunlight and shadow.