His senior season, Holden again started at left tackle and earned All-Southeastern Conference 2nd team(coaches) honors.

[1][2] Holden graduated from Vanderbilt University in December 2016 with a degree in Human and Organizational Development, where he was a member of Pi Kappa Alpha.

Prior to the combine, Holden played guard at the East–West Shrine Game and the Senior Bowl.

Holden has an impressive week of practices leading up to the shrine game and was identified by NFL analyst as one of the players who raised his draft stock.

[4] Holden also attended Vanderbilt's Pro Day, but was satisfied with his combine performance and opted to only do positional drills.

New England Patriot's head coach Bill Belichick and representatives from 28 NFL teams attended Vanderbilt's Pro Day to scout Holden, Zach Cunningham, and nine other players.

[5] At the conclusion of the pre-draft process, he was projected to be a third or fourth round draft pick from the majority of scouts and analysts.

[22] He was waived during final roster cuts on September 5, 2020, and re-signed to the practice squad the next day.

[34] On November 22, 2022, Holden signed to the Cleveland Browns practice squad[35] He was released on December 2.