[1] Built around 1853 for William Anderson, the first Washtenaw County Sheriff, the house is a well-preserved surviving example of Greek Revival architecture in Southeast Michigan.

The church built a larger building on the grounds in the 1950s, and entered into a unique joint venture with Reform Jewish congregation Temple Beth Emeth in 1974, forming Genesis of Ann Arbor.

He purchased two parcels of land on Packard Road in 1831, which was at the time outside the Ann Arbor city limits in Pittsfield Township.

[2] Wilson constructed a grand Greek Revival-style house in downtown Ann Arbor in 1839, the same year that Anderson's term as sheriff ended.

[4] Wisdom attended the University of Michigan Medical School, graduating in 1923, and interning at the Women's Homeopathic Hospital in Philadelphia.

Wisdom became the executive director of the Ann Arbor Maternal Health Clinic on North Main Street in 1935, and purchased the Anderson House in 1937 for her residence and medical practice.

[7] Wisdom lived in the Anderson House with her longtime partner Gertrude Griffith, who was made joint tenant of the property in 1945.

[10] St. Clare of Assisi Episcopal Church began leasing space to Temple Beth Emeth, a newly formed Reform Jewish congregation, in 1970.

The lease grew into an equal partnership of two congregations sharing a house of worship, and Genesis of Ann Arbor was formed as a separate entity to manage the property and facilitate dialogue.

[11] A 1994 addition to the Genesis of Ann Arbor building added a similar small chapel for the exclusive use of Temple Beth Emeth.

The house was leased out as commercial office space beginning in 1982, and was occupied by multiple organizations, including a real estate firm and a youth soccer league.

The Back Door Food Pantry began as a program of St. Clare, and since 2010, has also been supported by Temple Beth Emeth and the Ann Arbor Muslim community.