William Bliss Pine (December 30, 1877 – August 25, 1942) was an American businessman who served as United States Senator from Oklahoma.

Born in Illinois, he moved to Kansas and finally Oklahoma, where he became a prominent businessman and oil producer.

[1] He became a traveling salesman with the D. M. Osborne Company, which took him to Neosho County, Kansas, where he got caught up in oil fever.

Called a "regular Republican" for his positions on the economy, the senator sided with the "Progressive" part of his party on matters related to agriculture and foreign affairs.

[1] He supported protective legislation for the petroleum industry and fought to bring federal road projects to Oklahoma.