[3] They began their business in Malden and, in 1849, he moved to New York City where Isham formed a partnership with George Palen and Isaac H. Bailey.
"[3] [5] Isham was a benefactor of the Mount Washington Presbyterian Church and served as a trustee of the Dyckman Library.
[6] In 1862, he rented the former house and estate of the late Dr. Floyd T. Ferris, in uptown Manhattan, as a summer residence.
The house was situated at the highest point on the property and afforded the Ishams expansive views of the Hudson and Harlem Rivers and the Spuyten Duyvil Creek.
[10] Together, William and Julia were the parents of:[1] Isham died at the age of 81, at his home at 5 East 61st Street in Manhattan, on March 23, 1909.