William Creed Wampler Sr. (April 21, 1926 – May 23, 2012) was an American newspaperman, businessman and Republican politician who served multiple terms in the United States House of Representatives.

[1][2] Born in Pennington Gap near the center of Lee County, Virginia, on April 21, 1926, to hardware store proprietor John Sevier Wampler and his schoolteacher wife, the former Lilian May Wolfe, the child nicknamed Bill Wampler attended the public schools in Bristol, Virginia.

After losing his campaign for reelection in 1954 to the 84th Congress, Wampler received a job working for the U.S. Atomic Energy Commission during the administration of President Dwight D. Eisenhower, which he held from January 1955 to March 1956.

However, Wampler returned to Virginia to assist at the family furniture and carpeting businesses as well as to campaign again.

As the Byrd Organization collapsed along with its policy of massive resistance to the 1954 and 1955 school desegregation decisions of the United States Supreme Court in Brown v. Board of Education, Wampler won election to the 90th Congress, defeating William Pat Jennings by winning 53.7% of the votes cast.

However, Wampler narrowly lost his re-election campaign in 1982 to Democrat Frederick C. Boucher, who won 50.4% of the votes cast.

In 1982, Democrat Rick Boucher defeated the 16 year incumbent Wampler by 1,100 votes, and won re-election for decades.