[1] He was admitted to the bar and entered private practice in Chillicothe, Ross County, Northwest Territory (State of Ohio from March 1, 1803) from 1798 to 1803.

[2] He was elected as an Adams Republican from Ohio's 6th congressional district to the United States House of Representatives of the 20th United States Congress and served from March 4, 1827, until his resignation in 1828 to accept a federal judicial position.

[2] Following his first two terms in Congress, Creighton was President of the Chillicothe Branch of the Second Bank of the United States in 1817.

[1] Creighton received a recess appointment from President John Quincy Adams on November 1, 1828, to a seat on the United States District Court for the District of Ohio vacated by Judge Charles Willing Byrd.

[1] The Senate on February 16, 1829, passed a resolution that it was “not expedient to fill the vacancy at the present session of Congress.”[2] Following the termination of his federal judicial service, Creighton resumed private practice in Chillicothe from 1833 to 1851.