On his father's side he was descended in the female line from the Hon.

He was a major landowner in the Manchester area and a benefactor to Chorlton-cum-Hardy.

Lord Egerton married Lady Charlotte Elizabeth, daughter of John Loftus, 2nd Marquess of Ely, on 18 December 1830.

Egerton survived her by five years and died in February 1883, aged 76.

He was succeeded in the barony by his eldest son Wilbraham, who was created Earl Egerton in 1897.