William Henry Twenhofel (16 April 1875 – 4 January 1957) was an American sedimentary geologist who wrote a landmark text Treatise on Sedimentation (1926) which went into more editions.
The Society of Economic Paleontologists and Mineralogists instituted the Twenhofel Medal in his memory.
From 1896 he taught in local schools in winter and worked in summer to earn for his livelihood.
In 1902 he went to the National Normal School in Lebanon, Ohio, receiving a BA in 1904.
Along with Raymond C. Moore he was one of the founding associate editors for the Journal of Sedimentary Petrology from 1931.