[4] Weightman amassed a large fortune through shrewd investments, derived from his manufacturing enterprise, estimated at $51.8 billion in 2014 adjusted value.

[5] At the turn of the 20th century, he was "the largest individual owner of Philadelphia real estate,"[6] having purchased hundreds of acres of farms and built whole neighborhoods of middle-class housing.

Hale also designed Weightman's country house, Ravenhill (1887), built in the West Germantown section of Philadelphia, on a ridge overlooking the Wissahickon Creek.

Following her husband's death in 1903, she was admitted as a partner in Powers & Weightman, "the only woman in the United States to hold such a position of responsible trust".

[citation needed] The University of Pennsylvania gymnasium, Weightman Hall (1903–05, Frank Miles Day, architect), adjacent to Franklin Field, is named for him.