[2] In 1867 he returned to his alma mater in Edinburgh to become third principal of the Dick Veterinary College, replacing the brief principalship of Colonel James H. B. Hallen FRSE who was urgently called to India to address an outbreak of cattle plague.
[4] In January 1869 he and fellow veterinary professor Allen Dalzell were sued in the Scottish Court of session by a former colleague, John Adam McBride, leading to a great deal of ill-will in the college.
[6] In 1883, due to growing success, the college commissioned William Hamilton Beattie to design a purpose-built building on the east side of Elm Row, at the head of Leith Walk where it remained until closure in 1904.
Following his father's death the college lost momentum and in 1904 William Owen Williams moved to Liverpool to set up a new veterinary college, being officially Professor of Veterinary Medicine and Surgery at Liverpool University.
Williams was one of twenty "shadow portraits" created in 2005 of the various Dick Vet Principals.