The William and Margaret Mecum House is located at 168 Lighthouse Road in Pennsville Township of Salem County, New Jersey, United States.

Built in 1737, the house was added to the National Register of Historic Places on March 5, 2018, for its significance in architecture.

[3] The house is part of the Traditional Patterned Brickwork Buildings in New Jersey Multiple Property Submission (MPS).

It was expanded c. 1770 by his son and has the initials WM and the date 1737 in the gable brickword.

The two-story house uses Flemish bond brickwork and features Georgian architecture.