The William and Mary Quarterly is a quarterly history journal published by the Omohundro Institute of Early American History and Culture.

[citation needed] Currently in its third series, the Quarterly is the leading journal for studying early American history and culture.

Geographically, it focuses on North America—from New France and the Spanish American borderlands to British America and the Caribbean—and extends to Europe and West Africa.

Though grounded in history, it welcomes works from all disciplines bearing on the early American period—for example, literature, law, political science, anthropology, archaeology, material culture, and cultural studies.

The journal is named after the College of William and Mary where it was founded in 1892.