William Mitchell (December 1, 1889 – November 23, 1973) born in Pleasant Grove, Mississippi,[1] was a pitcher for the Cleveland Naps/Indians (1909-1916) and Detroit Tigers (1916-1919).

In 11 seasons, he had an 84–92 record in 276 games pitched with 93 complete games, 16 shutouts, 4 saves, 1632 innings pitched, 605 walks allowed, 921 strikeouts, 75 hit batsmen, 48 wild pitches and a 2.88 ERA.

He was the first pitcher to strike out Babe Ruth which happened at Fenway Park.

He died in Sardis, Mississippi, at the age of 83.

This biographical article relating to an American baseball pitcher born in the 1880s is a stub.