[3][4] Pwaisiho was ordained a deacon in 1974 and a priest in 1975; he was Chaplain to Norman Palmer, Archbishop of Melanesia and to the Police in Honiara, both in 1976.

He then became curate (the first missionary priest from Melanesia), at Mission Bay, New Zealand (1977–1978) then Chaplain and Tutor, Bishop Patteson Theological College in Kohimarama (1979–1980) where he himself had trained.

His final post before appointment to the episcopate was as Dean of St Barnabas Provincial Cathedral, Honiara (1980–1981).

[7] In Cheshire, he has served as Chaplain to John Richards, High Sheriff (2002–2003); as Honorary Chaplain to the national charity CrimeBeat (2004–present); and a Member of the Ethnic Minority Independent Advisory Group for Cheshire Constabulary.

He became an Officer of the Order of the British Empire (OBE) in 2004 and is also a member of Melanesian Mission UK and of the Churches Together in Britain and Ireland Pacific Forum.