The Wilmington Historic District is a national historic district located at Wilmington, New Hanover County, North Carolina.

The district developed after Wilmington was laid out in 1737, and includes notable examples of Queen Anne and Bungalow/American Craftsman style architecture.

Located in the district are the separately listed City Hall/Thalian Hall and Alton Lennon Federal Building and Courthouse.

Other notable buildings include: It was listed on the National Register of Historic Places in 1974, with a boundary increase in 2003.

This article about a property in New Hanover County, North Carolina on the National Register of Historic Places is a stub.