Located opposite Mumbai's Girgaon Chowpatty, the college building was constructed in 1889 and designed by John Adams in the domestic Victorian Gothic style.

Margaret started a school for girls in 1829 at Ambroli House in Girgaum at Mumbai, with Marathi being the chief medium of instruction and learning.

Short prayer services that include Hymns and Bible reading are conducted every day during the morning and the afternoon recess in the chapel.

They acquired an impressive victory over the rest of Mumbai teams and went on to play in the National Blind Football Match held in Cochin, Kerala.

[19] There are books on varied subjects including general studies, history, sociology, political science and economics in addition to atlases and maps.

In 2011, Vaibhav Purandare, journalist at Hindustan Times and author of The Sena Story visited the college and spoke to the students about corruption, politics and other current issues.

These include Athletics, Football, Cricket, Rugby, Hockey, Badminton, Weight Lifting, Boxing, Gymnastics, Table Tennis, Carrom, Chess etc.

Sir Shapurji Bharucha played a major role in the process, donating INR 10,000/- to meet the cost of construction.

Since then, sporting activities of the college have expanded immensely, with the school producing sportspersons at state, national and even international level.

Former Indian Cricketer, Dilip Sardesai; Woman International Master in Chess, Rohini Khadilkar and Arjuna Awardee for proficiency in Yachting, Jeejee Unwalla have all been affiliated to the Wilson College Gymkhana.

Revived in 2001 and guided under the norms of the University of Mumbai, the National Service Scheme (NSS) group of Wilson College forms a part of Independence Day celebration in New Delhi.

The Centre empowers students to deal with emotional and psychological stressors, problems related to peer/parental pressures, identity and managing inter-personal relationships.

Apart from dealing with emotional and stress-related issues, the Counselling Centre provides vocational guidance as well, which involves giving out information on various career options, academic courses, eligibility criteria and suitable institutions.

With "the quest for sensible, greener options" as its motto, the major activities of the WCNC include conducting nature trails to wilderness areas in Mumbai, usually from July to January, organising overnight treks on the weekends to biodiversity hotspots around Mumbai and 7- to 14-day nature camps to noteworthy national parks and wildlife sanctuaries in India.

Songs like "And You Say the Battle is Over" by John Denver, "Garbage" by Pete Seger, "Blowin' in the Wind" by Bob Dylan and "Don’t Go Near the Water" by Johnny Cash rank high on the club playlist.

The central idea behind these camps is to create awareness about environmental issues and to better understand the culture and traditions of the places visited.

The WCNC had formed a body exclusively for its alumni in 1981 called the Naturalia Wilsonica, which enabled and encouraged ex-students to continue visiting the wilderness.

The Mission of the Students' Council is as follows: Wilson College offers five unaided or professional undergraduate degree courses viz.

In June 1999, the University of Mumbai introduced the Bachelor of Mass Media (BMM) Course, a three-year integrated degree program.

This exposure enables the students to make a connect between theories learnt during classroom sessions and its application in real-life situations in organisations.

In this three-year integrated degree programme, industrial visits, corporate guest lectures and industry-based projects form an imperative part of the curriculum.

Department of Biotechnology has a Certificate Course in Molecular Biology Techniques for students coming from all streams of life sciences.

BSc in Computer Science was introduced by Wilson College in academic year 1999–2000 to train students for the Information Technology field.

Polaris is the oldest mass media festival in Mumbai, dating back to 2001 and takes place in July every year.

This includes film maker and Chief Creative Officer of the advertising agency Lowe Lintas, R. Balki, Journalist Jerry Pinto, Ad guru Prahlad Kakkar, theatre personality Dolly Thakore as well as famous celebrities such as Irfan Khan, Arjun Kapoor, Anil Kapoor, Ileana D'cruz among others.

Adorea has played host to various management professionals such as Vithal Kamat, Owner of the Orchard Group of Hotels, as well as noted film personalities such as Boman Irani.

The Official website for Adorea is http://www.adorea.in The students of Wilson College along with the help of some faculty members started a programme called "Rainbow" in 1997.

Rainbow represents the seven sister states, Arunachal Pradesh, Assam, Manipur, Meghalaya, Mizoram, Nagaland, Tripura and also Sikkim.

There was also screenings of two documentaries: "Mizorams Freedom Struggle", "The dying culture of Meghalaya" and a film "Adayja" (The Fight), a movie that won the prestigious Silver Peacock award.

Wilson College has been home to a number of famous people including writers, scholars, freedom fighters, politicians, businessmen, sportspersons, artists etc.