[2][3] 17 Wimpole Mews was the home of the osteopath Stephen Ward (1912–1963)[4] in the early 1960s.

He acted as "landlord" to Christine Keeler (1942–2017)[5] and Mandy Rice-Davies (1944–2014).

Keeler had affairs with the politician John Profumo (1915–2006), Secretary of State for War, and the Soviet naval attaché and spy Captain Yevgeny Ivanov (1926–1994), resulting in the Profumo affair scandal in 1963.

In December 1962, Johnny Edgecombe (1932–2010), a former lover of Christine Keeler, fired five shots at the lock of 17 Wimpole Mews using a handgun that Keeler had given him, triggering events that led to the scandal.

[6] The experiences of Christine Keeler were dramatised as the six-part television serial The Trial of Christine Keeler and broadcast by the BBC during December 2019 to January 2020, featuring events in Wimpole Mews.