Wisłok Wielki (Polish pronunciation: [ˈviswɔk ˈfjɛlkʲi]) is a village in the Bukowsko Upland mountains.

The historical record relates that in 1361 the brothers Peter and Paul, "from Hungary," as feudal landholders, "owned" Wisłok Wielki, along with Bukowsko and several other area villages (see Nowotaniec, Zboiska, Humniska etc.).

Located in the Ruthenian voivodeship of the Polish-Lithuanian Commonwealth, Polish Kingdom and later Austria-Hungary Empire, the village, isolated and remote, remained largely impervious to change.

During World War I, the region would be at the epicentre of the conflict between the Austro-Hungarian and the Russian empires, with several small battles conducted in the vicinity of the Wisłok Wielki.

During the 1930s, although there were tensions over issues of language, education and official assimilation, communal relations at the local level between Lemkos and Poles in the Sanok County were favorable.

The Byzantine-styled village church in Lower Wisłok Wielki, originally built in 1785, was destroyed in 1946, although the remnants of a cemetery are still visible.