The name comes from the River Wisłoka, which flows by the town of Dębica (south-east Poland, 110 kilometers east of Kraków).

The club is also renowned for soccer players such as Leszek Pisz, Mirosław Kalita and Waldemar Piątek, who started their careers there, boxers (such as vice-champion of Europe, Roman Gotfryd), and bicycle racers.

Association football, the most popular of all sports in Poland, followed some time later – around 1909 (though there is no credible source to confirm this date).

The best decade for the club were the 1970s, when its departments were separately sponsored by Dębica's main factories, and its athletes won medals during various national and international competitions.

Supporters of Wisłoka are allied with fans of two other clubs – Górnik Zabrze (since September 1988) and Siarka Tarnobrzeg (since November 2007).

Four years later, Stal merged with Wisłoka, and in June 1963 the much stronger team emerged, that won games in Rzeszów's regional league, advancing six points before Czuwaj Przemysl.

Dębica's opponents included Victoria Jaworzno, Star Starachowice, Orzeł Rapid (which later became GKS Katowice) and Górnik Sosnowiec.

In 1966, Wisłoka's officials brought in a veteran midfielder Ludwik Poświat, who, as a 17-year-old, talented teenager, had won the Championships of Poland (in 1948, with Cracovia).

Wisłoka, sponsored by DZOS Stomil (today – Tire Company Dębica) spent seven years in the second division.

The team played at the third tier, group 8th (south-east Poland), for most time placing in the upper half of the table.

Some changes took place, after which the White and Greens returned to the third tier in June 1988, finishing before both BKS Bochnia and Okocimski Brzesko.

In the 1990–91 season, Wisłoka again, after several years, won promotion to the II liga, group south, finishing ahead of Sandecja Nowy Sącz and Cracovia.

The team, led by coach Jan Kasowicz during the whole season, proved its quality, winning 14 games, drawing 7, and losing only 3 (goals 40–13).

At the end of the following 2005–06 campaign, the White and Greens finished on the first position in the league, three points ahead of Izolator Boguchwała, and won promotion to the third Division.

Wisłoka, a team which has never managed to qualify to the first division, is an example of a club whose biggest successes are associated with the Polish Cup.

Finally, on 31 August 1989 Wisłoka Dębica tied 0–0, with Górnik Zabrze losing 4–5 on penalty shootout.

Finally, in the quarterfinals of the Polish Cup, played on 10 and 23 March 1993, Wisłoka lost twice to Ruch Chorzów II; 0–1 at home, and 0–2 away.

Ruch was represented by players such as Radosław Gilewicz, Waldemar Fornalik, Mariusz Śrutwa, Dariusz Gęsior, Jacek Bednarz, Piotr Mósor, among others.

In fact, the club's biggest successes are associated with a completely different sport – wrestling, Greco-Roman style.