Born in Fajardo, Puerto Rico, Wise moved to the Bronx, New York, where his parents resided with his two older brothers Juan & Jose.

While Daddy-O performs the vocals, Wise gives his version of "Impeach the President," which happens to be the very first time that a human beatbox was heard adding a song-like rhythm to the beat that was coming out of his mouth on the song "Faye"[citation needed] which was on the group's first album, On Fire (1986).

With Stetsasonic, Wise toured the world with rap acts like Run-DMC, LL Cool J, Whodini, Eric B.

In 1989, Wise (with fellow Stetsasonic members Daddy-O, Delite, and Fruitkwan) participated in KRS-One's Stop the Violence Movement, an assembly of hip hop artists including Kool Moe Dee, Heavy D, MC Lyte, Public Enemy, and Doug E. Fresh.

This artistic collaboration yielded the posse cut "Self Destruction", a protest song decrying black-on-black violence and media stigmatisation of all hip hop as violent.