Wise Guys is a 1986 American black comedy crime film directed by Brian De Palma and produced by Aaron Russo from a screenplay written by George Gallo and Norman Steinberg.

It stars Danny DeVito and Joe Piscopo as two small-time mobsters from Newark, New Jersey, and features Harvey Keitel, Ray Sharkey, Lou Albano, Dan Hedaya, and Frank Vincent.

"[3] Italian American Harry Valentini and his Jewish friend and next-door neighbor Moe Dickstein occupy the bottom rung of Newark Mafia boss Anthony Castelo's gang.

Making a living by doing Castelo's lowest jobs (such as looking after his goldfish, testing out bullet-proof jackets, or checking the boss's car for bombs) the two men dream of opening the world's first Jewish-Italian delicatessen.

After using Acavano's credit cards to pay for a luxury stay in a hotel owned by their old friend Bobby DiLea, the two go to Uncle Mike's house to ask for help.

Moe seems perturbed, but the film ends with their dream realized as the two stand in their Jewish-Italian delicatessen at DiLea's hotel.

If I’m not in front of a live crowd ingratiating them where my full strength is … I can play a character, and I should’ve probably done that with Wise Guys.

[7] A positive review came from The New York Times, with Walter Goodman calling it amusing and fresh before concluding that "Everything works.

"[8] Roger Ebert was similarly enthusiastic, giving the film three-and-a-half stars out of four and writing, "Wise Guys is an abundant movie, filled with ideas and gags and great characters.

"[9] Gene Siskel of the Chicago Tribune awarded a perfect grade of four stars and raved, "Big laughs, foul language to the point of absurdity and one hilarious, screaming performance atop another combine to make 'Wise Guys' one of the funniest times you will have at the movies this year.

"[10] A negative review in Variety stated, "Gone are the flamboyant excesses that made a DePalma film instantly recognizable.

"[11] Patrick Goldstein of the Los Angeles Times wrote, "Directed by Brian De Palma with an uncharacteristic twinkle in his eye, the film offers such a likeable gallery of cement-heads that we're in no mood to carp about the movie's creaky storyline, belabored gags or meandering chase scenes.

"[12] Paul Attanasio of The Washington Post remarked, "There is plenty of dumb stuff in 'Wise Guys,' a rambunctious comedy about two screwballs on the loose, probably more than anyone should stand for.