Wishart Flett Spence CC OBE (March 9, 1904 – April 16, 1998) was a puisne justice of the Supreme Court of Canada.

He then received a Bachelor of Arts degree in political science from the University of Toronto in 1925, studied law at Osgoode Hall Law School, where he received the gold medal for finishing first in his class, and was called to the Ontario Bar in 1928.

Spence practised law in Toronto and was a part-time lecturer at Osgoode Hall.

In 1966, he chaired the royal commission investigating the Munsinger Affair, which involved allegations that an East German spy had been sleeping with Canadian Cabinet ministers.

Spence criticised the way the Diefenbaker government had handled the matter, but found no evidence of criminal wrongdoing or security breaches.