Wissinoming is a neighborhood in the Near Northeast section of Philadelphia, United States.

It was the site of locomotive builder Matthias Baldwin's estate "Wissinoming", which was located near Tacony and Van Kirk Streets.

The current Wissinoming is bordered by Mayfair on the west and Tacony on the north, Bridesburg on the south (below Bridge Street), I-95 and the Delaware River on the east, and Frankford on the southwest (below Bridge Street).

The name derives its name from a Lenni Lenape term meaning “where the grapes grow”.

Philadelphia's 15th Police District (located roughly at Levick Street and Harbison Avenue) covers Wissinoming.