The series focuses on Nico Wakatsuki, a teenage witch who, after completing her magical training, moves into a house with her childhood friend Morihito Otogi, a human-looking ogre.

[8] The February 6, 2023, chapter of the manga began a crossover with Shinohara's previous Weekly Shōnen Jump series, Sket Dance.

[17] Witch Watch has been licensed for simultaneous publication in North America as it is released in Japan, with its chapters being digitally launched by Viz Media on its Shonen Jump website.

[51][4] The series is set to premiere on April 6, 2025, on the Nichi-5 [ja] programming block on all JNN affiliates, including MBS and TBS, and will run for two consecutive cours.

[52] Crunchyroll and Netflix will be streaming the series worldwide alongside other platforms such as Hulu (United States), Animation Digital Network (several European territories) and Aniplus (South Korea).

[34] Timothy Donohoo of Comic Book Resources compared Witch Watch to Kouji Miura's Blue Box and Shigure Tokita's Don't Blush, Sekime-san!