[3] It is an homage to the 1995–1998 HBO sketch comedy series Mr. Show with Bob and David, which also starred Odenkirk and Cross.

W/ Bob & David shares many of the same supporting cast members and writing team of the earlier series, and its title is also a variation of that of Mr. Show.

Bob & David contacted Cyriak to create the opening sequence with a hands-off approach, only asking him to not make it specifically like standard TV credits but more like his viral YouTube videos.

His signature style of beat sequenced animations to original music compositions featuring morphing branches of elements from still photos and videos created in Adobe After Effects.

[6] is greatly inspired by, and has been compared to Terry Gilliam's animated sequences used in the British sketch comedy show, Monty Python's Flying Circus,[7] a significant inspiration for the show's creators and it's featured crossing of sketches with transitional videos and animated elements.

The site's critical consensus reads, "W/ Bob & David offers a long-overdue reunion between Mr. Show principals Odenkirk and Cross – and a suitably hilarious reminder of the reasons for their subsequent individual successes.