Witherspoon-Hunter House is a historic home located at York, York County, South Carolina.

It was built about 1825, and consists of a two-story, front section covered by a gable roof, with a one-story L-shaped rear annex.

The house is of frame construction and rests upon a raised brick basement.

[2][3] It was added to the National Register of Historic Places in 1978.

This article about a property in York County, South Carolina on the National Register of Historic Places is a stub.