Withington is a member of the Girls' Schools Association[2] and the Headmasters' and Headmistresses' Conference.

It was named North West Independent School of the Decade by The Sunday Times in 2021.

[4] Withington consistently ranks as one of the top schools in the country for academic results.

[5] Withington Girls' School was founded in 1890 by a group of eminent Manchester families who wanted the same educational opportunities for their daughters as were already available for their sons.

Pupils receive an outstanding education in accordance with the school's aims to help girls achieve an excellent standard of academic achievement, and to foster intellectual curiosity, a love of learning, independence of mind and individual responsibility.The school suffered a serious arson attack in August 2003, but took this as an opportunity to build new science labs, and has since built a new sixth form common room and additional classrooms.