[2] On 12 November 1849, the Shrewsbury and Birmingham Railway opened a temporary terminus to its line, at a location very close to the present station.

[3] The present station site was opened on 1 July 1852 by the Birmingham, Wolverhampton and Stour Valley Railway, a subsidiary of the London and North Western Railway (LNWR); it was named Wolverhampton Queen Street.

[6] Services over the former Grand Junction Railway line to Walsall (and thence to Lichfield City and Burton-on-Trent) ended in January 1965, this route being the only one from here to fall victim to the Beeching Axe.

The since replaced Wolverhampton station dated from 1964[7] when the High Level station was completely rebuilt by the architect Ray Moorcroft as part of the modernisation programme which saw the West Coast Main Line electrified.

As part of this scheme, most services on the OW&WR route from Shrewsbury were diverted here from Low Level (though a few peak-hour trains continued to serve the latter until March 1968); these then continued to Birmingham New Street via the Stour Valley line rather than via the ex-GWR line to Birmingham Snow Hill as before.

[9] Work on the £150 million redevelopment of the station finally began in 2018, and was expected to be completed in 2020, it included an extension of the West Midland Metro.

[13] The basic Monday to Saturday off-peak service in trains per hour (tph) is as follows: Avanti West Coast[14] 1 early morning service runs to Holyhead via Chester, Llandudno Junction and Bangor on Mondays to Saturdays.

Prior to the June 2024 timetable change, Avanti West Coast operated a daily direct service between Shrewsbury and London Euston.

CrossCountry[20] Transport for Wales Rail[21][22] West Midlands Railway also will run a direct Wolverhampton-Walsall service via Willenhall and Darlaston, expected to start in Winter 2025/26.

Ion Developments (previously Neptune Developments) were selected for the project and plan to create a major mixed used area that includes both bus and railway stations, a hotel, retail outlets, bars, cafes and offices.

Phase Two, which includes the railway station, canalside development, and a hotel, has commenced as of September 2018.

[27] On Friday 28 September 2018, work started on Wolverhampton's Railway Station, with the demolition on the Transport Police building.