Woodbine is a city in Harrison County, Iowa, United States, along the Boyer River.

[3] Woodbine was platted 1866 at the time the Chicago and North Western Railway was built through that territory.

There were 727 housing units at an average density of 543.9 per square mile (210.0/km2).

Hispanic or Latino persons of any race comprised 2.3% of the population.

There were 679 housing units at an average density of 530.5 per square mile (204.8/km2).

32.7% of all households were made up of individuals, and 20.1% had someone living alone who was 65 years of age or older.

There were 696 housing units at an average density of 614.6 per square mile (237.3/km2).

32.8% of all households were made up of individuals, and 21.8% had someone living alone who was 65 years of age or older.

The Harrison County Genealogical Society is headquartered in a one-room schoolhouse, Merry Brook School Museum, built in the 1870s.