[10] While foraging, wood mice pick up and distribute visually conspicuous objects, such as leaves and twigs, which they then use as landmarks during exploration.

During the colder months, wood mice do not hibernate; however, during severe winter seasons they can fall into a torpid state, a decrease in physiological activity.

Predators of wood mice include foxes, snakes, weasels, birds of prey such as owls, cats, and dogs.

[14] The wood mouse has a breeding season from February to October in which multiple matings occur between males and females, resulting in scramble competition.

Males possess a sac known as the cauda epididymis, which stores sperm and lies underneath the scrotal protrusion.

The aggregates of spermatozoa that result in form "mobile trains", which have experimentally been determined to possess better motility in the female reproductive tract.

The gestation period of wood mice is of 25–27 days and each female produces on average four young per year.