He was the first son and successor of Ulrich I, Duke of Brno (died 1092) and an unknown princess (probably of Slavic origin).
together later established a Benedictine monastery and its St. Procopius Basilica in Třebíč and prepared as mausoleum for the Brno-Znojmo branch House of Přemyslid.
Wratislaus himself probably initiated the establishment of the Royal cathedral chapter of St. Peter and Paul in Brno, formally created later in 1292.
Wratislaus initially ruled in the Brno part (the western one) of the duchy of Moravia, until 1129 when they were evicted illegitimately by Bretislaus II.
In 1104 his father and uncle together founded a Benedictine abbey in Třebíč whose convent church of St. Procopius was intended as their own dynastic mausoleum where they were both buried.